LifeLink Tissue Bank has earned a reputation for providing the highest quality allografts available in the industry. This is a result of our commitment to meeting or exceeding industry standards at every step of the process, from procurement to the distribution of each allograft. Each graft is carefully crafted and measured to adhere to our stringent standard of quality and specifications.
We are proud of our safety record and committed to maintaining these superior standards for the future. Our goal is to continue to improve technologies needed for patients in need of transplantation therapy.
Cleaning and Disinfection
LifeLink processing methods include the revolutionary Allowash® method which allows our allografts to be cleaner and safer while maintaining their clinical effectiveness. Viral inactivation studies indicate that the processing of allograft tissue using Allowash® technology is highly effective for the inactivation of both RNA and DNA enveloped viruses of the Retro, Flavi, and Herpes families.
Allowash® technology does not affect the osteoinductivity of bone allografts and adds a greater measure of assurance to physicians and patients. Although this technology is a visible breakthrough in the cleaning process, it will never act as a substitute for the strict donor-screening guidelines employed by LifeLink Tissue Bank.
Allowash Technology® involves a series of mechanical and reagent cleaning and disinfection steps to reduce any potential bioburden. This process includes the use of Allowash® solution, a combination of biological detergents that work in conjunction with traditional treatments such as alcohol and hydrogen peroxide to enhance the solubilization and removal of bone marrow, blood, and lipids (elements that may possibly act as a reservoir for disease transmission). In addition, antibiotics (Bacitracin and Polymyxin B) are also utilized in the processing of allografts. Tissue to be demineralized is further processed using Hydrochloric Acid and Sodium Phosphate Buffer.
Highly Trained Staff
The tissue recovery team and musculoskeletal processing technicians at LifeLink are dedicated and respectful of donors and their families. They understand the responsibility of honoring this precious gift. In some cases, a single tissue donor can provide over a hundred allografts to patients in need.
All LifeLink technicians are specially trained in specific tissue recovery processing procedures and adhere to AATB standards and Current Good Tissue Practices (CGTP) established by the FDA.
Initial training lasts three months and all activities are continually monitored and reviewed by the QA department. Re-training and education occurs on an on-going basis. Each technician is either AATB certified or works directly under the supervision of other Certified Tissue Bank Specialists until he/she meets the criteria for certification.
- State-of-the-art techniques are utilized to maintain tissue integrity and safety
- All packaging is completed in a class-100 clean room environment
- Freeze-dried allograft is placed in heat-sealed triple or double Tyvek™ envelopes
- Frozen allograft is packaged in triple or double Tyvek™ envelopes with inner most bag film on film
Freeze drying- A method that reduces the residual moisture level to equal to or less that 6% as recommended by the AATB. Freeze drying, also known as lyophilization, is the most common preservation method.
Freezing– A method in which grafts are packaged and stored at temperatures of -40 degrees Celsius or colder.